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Defend the Astral World! Once More, ZEXAL, The Combination of Hope and Wishes! is the one-hundred and twenty-second episode in the Yu-Gi-Oh! ZEXAL anime.

Yuma's feelings for Astral finally reach the Will of the Astral World, allowing a touching reunion between Yuma and Astral. On the other hand, Reginald, a.k.a. Nasch, who finally defeated Vector, now carries the power of Don Thousand and goes on a rampage. In order to stop Nasch from destroying the Astral World, Yuma and Astral recombine into ZEXAL (power) and confront Nasch. But when Yuma notices Nasch is actually his bud Shark, he begins to waver in the middle of the Duel...

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