Slifer, Slifer the Sky Dragon or Osiris the Sky Dragon may refer to any of the following:
- Slifer the Sky Dragon (original): The original illegal version.
- Slifer the Sky Dragon: The legal version.
- Slifer the Sky Dragon (DDM): The Dungeon Dice Monsters card.
- Roger Slifer (Yu-Gi-Oh! dub Executive Producer)
- Slifer the Sky Dragon, the character.
- Slifer Red: A dormitory in Duel Academy.
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