Ryo may refer to any of the following characters:
- Ryo Bakura, a character from the original Yu-Gi-Oh! series
- Ryo Marufuji, a character from Yu-Gi-Oh! GX, known an Zane Truesdale in the English version
- Ryo (Tag Force), a character from the Tag Force games
- Ryo Kato, a character from the Tag Force games, known as Rio in the English version
- Ryo Tajima, a character from Yu-Gi-Oh! ARC-V
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