- This card has several weaker and/or altered counterparts such as "Mystical Wind Typhoon", "Tornado", "Gust", "Twister", "Dust Tornado", "Wild Tornado", "Chain Whirlwind", "Double Cyclone", "Typhoon", "Cosmic Cyclone", "Galaxy Cyclone", "Twin Twisters" and the anime-exclusive "Psychic Cyclone".
- This card has been reprinted twenty-eight times, more than any other card.
- Many players joke that "MST negates", due to beginners often mistakenly believing that destroying a card negates its effect, and thus that "Mystical Space Typhoon" can be chained to an activated Spell or Trap Card to negate its effect.
- This was the first Spell Card ever to be released as Ghost Rare.
- This is one of the few cards that are known by two different names in the Spanish TCG, along with "Twin-Headed Behemoth" and "Blackwing Armed Wing".
- This is one of only two Spell cards to have appeared in all Yu-Gi-Oh! movies, along with "Polymerization".
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