- This monster appears in the artworks of "Success Probability 0%", "DNA Checkup", "Iron Core Specimen Lab", "Tour Bus To Forbidden Realms", "Compulsory Escape Device", and "Dr. Frankenderp".
- This card is based around the stock character The Mad Scientist in fiction. Many believe this character archetype sprouted from Mary Shelley's character Dr. Victor Frankenstein, from her novel Frankenstein. A monster card based on Frankenstein's monster, "Cyber-Stein", has a very similar effect, paying Life Points to Special Summon Fusion Monsters.
- In a similar vein, this card's Japanese name contains a pun: "Madō" translates into "magical", but can also be interpreted as a transliteration of "mad"; thus, "Magical/Mad Scientist".
- As seen in "Success Probability 0%", he seems to be friends with "Kozaky".
- The background of this card slightly resembles the processing chambers from the Guyver franchise.
- In card artworks, "Magical Scientist" is shown to have purple hair. However, his hair is brown in the anime.
- This card seems to have some relations to the Doktor in ARC-V in terms of design
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