- This card has 4 counterparts: "Crush Card Virus", "Eradicator Epidemic Virus", "Full Force Virus", and "Grinning Grave Virus".
- Of the 5 Viruses, "Deck Devastation" continues as the second of the 5 viruses Alphabetical Alteration patterns "D".
- The kanji 魔 on the viruses in this card's artwork means "demon."
- This is one of the three cover cards that are not monsters, the other ones are "Last Turn" that is featured on Legacy of Darkness and "Mask of Restrict" that is featured on Labyrinth of Nightmare.
- "Deck Destruction Virus" also has "DDV" as its initials, but is separate, and not considered a "Virus Card".
- The Japanese name of "Diabolos, King of the Abyss" refers to this card.
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