- "Cyber-Stein" and its Japanese name, meaning "Devil Franken", are both based off Frankenstein. In the novel, Victor Frankenstein revives a dead body comprised of body parts from several different bodies, much in the same way Fusion Monsters are comprised of Fusion Material monsters, explaining why "Cyber-Stein" summons Fusion Monsters.
- This monster shares a common naming convention with another monster based off of Frankenstein's monster- Number 22: Zombiestein. In the OCG, their names contain "Franken" (Cyber-Stein's OCG name is "Devil Franken" and Number 22's is "Fran Ken") while in the TCG their names contain "Stein" instead.
- This monster appears in the artwork of "Tour Bus To Forbidden Realms".
- Before Upperdeck Day only 18 of the SJC-EN001 card existed in the world. $20,000 USD was bid for a "Cyber-Stein" SJC-EN001 card on eBay, but the bidder didn't pay. The card was eventually resold for approximately $7,000 USD.
- In more recent years a copy or two have surfaced on card single sites for as low as $400 USD.
- "Cyber-Stein" was the first of only three cards to be banned during the middle of a banlist cycle, and not during the new banlist announcements. It was followed by "Dimension Fusion" and "Temple of the Kings".
- In the OCG, this card was Forbidden for sixteen formats before being Limited once more, the most of any card (surpassing "Magician of Faith"'s thirteen in the TCG).
- The Dark Beginning 1 version "Flame Swordsman" has its name misprinted as "Cyber-Stein".
- This card has the largest Life Point cost to activate of any card, barring cards with variable Life Point costs such as "Solemn Judgement" and "Backs to the Wall".
- This is one of only two Shonen Jump Championship Prize Cards to be banned, with the other being "Crush Card Virus".
- Coincidentally, both were printed as a Rare card in Dark Beginning Volume 2 and Turbo Pack: Booster One respectively. Before "Shrink" was printed as a common, this was the lowest rarity a Shonen Jump Championship Prize Cards was printed.