- "Blue-Eyes White Dragon", along with "Dark Magician", have the most alternative artworks.
- "Blue-Eyes White Dragon" is one of the only two cards in the game to have an official Chinese version, the other being "Dark Magician".
- This card is the cover card for the first TCG expansion, Legend of Blue Eyes White Dragon.
- This card was originally the main monster of Yugi Muto, but it was a last second decision to change this monster to Seto Kaiba's primary monster.
- "Blue-Eyes White Dragon" is the strongest Normal Monster in the game.
- Some people say that this card was the first Yu-Gi-Oh! designed card by Kazuki Takahashi, although this is not confirmed.
- This card has a counterpart, "Red-Eyes Black Dragon". Though BEWD is technically more powerful, the two dragons are similar in having different forms, including corresponding forms, like "Blue-Eyes Shining Dragon" and "Red-Eyes Darkness Dragon". Another counterpart is the White Night Dragon.
- Blue-Eyes White Dragon has a toon version, "Blue-Eyes Toon Dragon".
- "Blue-Eyes White Dragon" is featured in the artwork of "Burst Stream of Destruction", "Dimension Explosion" & "Ancient Rules" and barely in the background of Meteor Stream.
- The attack of this monster is named "Burst Stream of Destruction" . A Spell support card of the same name has also been released in the game. However, in the dubbed anime, the attack is called "White Lightning"
- Kisara carried the spirit of this card, but then gave it to Priest Seto in order to set him free from Aknadin's control.
- In Yu-Gi-Oh! The Falsebound Kingdom, the three Blue-Eyes White Dragons are named Azrael, Ibris, and Djibril.
- This card can be seen on the Tablet of Lost Memories as Priest Seto's monster.
- Blue-Eyes White Dragon has its very own Tuner Monster, The White Stone of Legend.
- The White Stone of Legend and the dragon displayed in the card Paladin of White Dragon are both younger versions of Blue-Eyes White Dragon.
- This card is Seto's Signature Card. It shares its 3000 ATK power with the rivals of other series, which are Chazz's Armed Dragon LV10 and Jack's Red Dragon Archfiend. It shares both ATK and 2500 DEF with Greiger's Flying Fortress SKY FIRE. In addition, many trump cards of other archetypes also share the same ATK and DEF (such as Horus, Judgment Dragon, and Volcanic Doomfire), and often the same type too. In rare cases, the monster is identical to Blue Eyes save for the name and effect.
- This monster was the first card to ever have an alternate art.
- This is also the first card to have a "Malefic" counterpart, Malefic Blue-Eyes White Dragon.
- In some Yu-Gi-Oh! video games, this card has an ally, the Mystical Elf, which can increase the attack and defense of this card by 500 points.
- In the GBA Yu-Gi-Oh! games, there is an alternate card number for the Blue-Eyes, 80906030
- This card has been realeased in every one of the major raritys except for Common.