- "Blue-Eyes White Dragon", along with "Dark Magician", and "Red-Eyes B. Dragon" have the most alternative artworks, with 5 different artworks, although in the TCG this card is the only one with all 5 released.
- "Blue-Eyes White Dragon", along with "Dark Magician", are the 2 cards that has been printed in all rarities other than Ultimate Rare. (With common edition released at Structure Deck: Dragons Collide.)
- "Blue-Eyes White Dragon", along with "Dark Magician", are the only 2 cards in the game to have an official Chinese version.
- This card is the cover card for the first TCG expansion, Legend of Blue Eyes White Dragon.
- This card was originally intended to be the main monster of Yugi Muto, but it was a last second decision to change this monster to Seto Kaiba's primary monster.
- "Blue-Eyes White Dragon" is the strongest Normal Monster in the game.
- "Blue-Eyes White Dragon" has a toon version, "Blue-Eyes Toon Dragon".
- "Blue-Eyes White Dragon" has a corrupted counterpart, "Malefic Blue-Eyes White Dragon".
- "Blue-Eyes White Dragon" is featured in the artwork of "Burst Stream of Destruction", "Dimension Explosion", and barely in the background of "Meteor Stream".
- The attack of this monster is named "Burst Stream of Destruction". A Spell support card of the same name has also been released in the game.
- In Yu-Gi-Oh! The Falsebound Kingdom, the three "Blue-Eyes White Dragon"s are named Azrael, Ibris, and Djibril.
- This card can be seen on the Tablet of Lost Memories as Priest Seto's monster.
- "Blue-Eyes White Dragon" has its very own Tuner monster, "The White Stone of Legend".
- "The White Stone of Legend" and the dragon displayed in the card "Paladin of White Dragon" are both younger versions of "Blue-Eyes White Dragon".
- "The White Stone of Legend" → "Paladin of White Dragon" → "Blue-Eyes White Dragon"
- This card is Seto's signature card. It shares its 3000 ATK power with the rivals of other series, which are Chazz's "Armed Dragon LV10", Jack's "Red Dragon Archfiend", and Kite's "Galaxy-Eyes Photon Dragon". In addition, many trump cards of other archetypes also share the same ATK and DEF (such as "Horus", "Judgment Dragon", "Stardust Dragon/Assault Mode" and "Volcanic Doomfire"), and often the same Type as well.
- This monster was the first card to ever have an alternate art.
- In some Yu-Gi-Oh! video games, this card has an ally, the "Mystical Elf", which can increase the ATK and DEF of this card by 500.
- In the GBA games, there is an alternate card number for this card - 80906030.
- Blue-Eyes' physical appearance may be a reference to the Dungeons & Dragons deity Bahamut, God of Metallic Dragons who is described as having silver-blue scales and blue eyes.
- This card in Gold Series: Haunted Mine will make it the first "Ghost Rare" Normal Monster as well as the first "Gold Rare" Normal Monster.
- This card is based on the Chinese Legend "Pai Lung"
- "Blue-Eyes White Dragon" has a Match Winner and Xyz version, "Legendary Dragon of White".