- This card can be searched by "Dogu", "Single Purchase", "Temple of the Kings", "Transmodify", "Rescue Ferret", "BOXer", "Frontline Observer", "Pyramid Turtle", "Diamond Core of Koa'ki Meiru" and "Iron Core Specimen Lab".
- The self-destruction of most "Koa'ki Meiru" monsters, including this card itself, are attached to maintenance costs, therefore are not counted as card effects and cannot be insured against with this card.
- "Koa'ki Meiru Prototype" is the exception - its destruction in place of a "Koa'ki Meiru" monster that fails to meet its maintenance cost is treated as a card effect, thus, this card can maintain itself by banishing a "Koa'ki Meiru" in your Graveyard to prevent "Prototype" from destroying itself.
- "Pyramid of Wonders" can be used to insure against the self-destruction of this card, because it does not state that it must be an effect that destroys the monster.
- If this card would be destroyed by a card effect, you can chain a Spell Speed 2 effect that adds a "Koa'ki Meiru" monster to your Graveyard. "Burial from a Different Dimension" can make use of already-banished "Koa'ki Meiru" monsters as protection.