Traditional Format[]
- This card can be searched by "Dark Sage", "Ancient Gear Drill", "Alchemic Magician", "Angmarl the Fiendish Monarch", "Left Arm Offering", "Watch Dog" and "The Despair Uranus".
- Very useful in an "Exodia" Deck when combined with "Manticore of Darkness" or "Fox Fire". An infinite loop can be set up with "The Wicked Worm Beast" and "Dark World Grimoire".
- In a Dragon Deck, this card can be used in conjunction with "Return of the Red-Eyes" or "Azure-Eyes Silver Dragon" to draw 1 card each turn in a small controlled loop. However, "Return of the Red-Eyes" can also summon on your opponent's turn.
- If you summon "Destiny HERO - Disk Commander" from the Graveyard while you control this card, you will draw 3 cards instead of 2.
- This card also works well in a "Dark World" Deck. When a "Dark World" monster is revived from the Graveyard, the effect of "Card of Safe Return" automatically activates, leaving the opponent no chance to counter its Special Summon with cards like "Bottomless Trap Hole" or "Torrential Tribute".
- This card works extremely well in a "Quickdraw Turbo" Deck. "Junk Synchron" Special Summons from the Graveyard "Quillbolt Hedgehog", "Doppelwarrior" or "Synchron Explorer". "Level Eater" Special Summons itself from the Graveyard by lowering the Level of a Synchro Monster or "Quickdraw Synchron". "Quillbolt" can also Special Summon itself from the Graveyard if you have a Tuner monster on the field. "Synchron Explorer" can Special Summon "Quickdraw" or "Junk" from the Graveyard. In all of these situations, you will be able to draw a card.
- This card can combo with "Green Baboon, Defender of the Forest".
- This card is a need in any Zombie Deck.
- This card works well with "Solemn Wishes". When the effect of "Card of Safe Return" activates, its controller will gain 500 Life Points.
- This card works very well with cards like "The Creator", "Doom Shaman", "Red-Eyes Darkness Metal Dragon" and "Gigaplant".
- This card works in tandem with the effect of "Stardust Dragon", "Infernal Dragon" or "Destiny HERO - Fear Monger".
- This cards also works with Spell or Trap cards like "Call of the Haunted", "Monster Reborn", "Premature Burial", "Battery Charger", "The Shallow Grave", etc.
- In a DARK-themed Deck, this card is very important. Since the Deck's main power is Graveyard Control, using cards like "The Dark Creator", "Dark Nephthys" and "Dark Horus" to Special Summon from the Graveyard repeatedly.
- In a "Lightsworn" Deck, this card also useful; e.g. by using the effect "Lumina, Lightsworn Summoner" to Special Summon a "Lightsworn" monster while "Card of Safe Return" is active, its controller will be able to draw, increasing their chances of drawing "Judgment Dragon" before it is milled by the effect of a "Lightsworn" monster.
- This card is useful in "Inca" and Revival of the Great Dragon/Rise of the Dragon Lords Deck which focus on Special Summoning from the Graveyard.
- This card combos well with "Ojama Country"; its controller will draw 1 additional card every turn by discarding one "Ojama" card and reviving another one in the Graveyard.
- Using this card in a Gemini monster Deck that utilizes cards that Special Summons from the Graveyard (example: "Blazewing Butterfly", "Supervise", "Black Brutdrago" or "Phoenix Gearfried") can increase the speed of getting vital cards.
- Using the Faultroll Loop in combination with this card creates an infinite draw cycle because "XX-Saber Ragigura" can be Special Summoned from the Graveyard when "XX-Saber Faultroll" is Special Summon from the hand, allowing its controller to draw a card.
- This card is useful with "Malice Doll of Demise" and "Ectoplasmer".
- This card can make the "Plaguespreader Hedgehog" loop endless if your control 1 "Imperial Iron Wall". Use the effect of "Plaguespreader Zombie" to Special Summon itself from the Graveyard, then draw again the same card returned to the top of your Deck. After that, use the effect of "Quillbolt Hedgehog" to Special Summon itself from the Graveyard too, then, you can both of these monster to Synchro Summon 1 Level 4 monster from your Extra Deck or use them to Xyz Summon Rank 2 monsters. If you use them to Synchro Summon monster, you can keep using them on Level 4 monster like "Armory Arm", "Phonon Pulse Dragon" and "Balmung, Fighter from the Underworld" and tune them to Synchron Summon horrors like "Shooting Quasar Dragon" or "T.G. Halberd Cannon".
- Alternatively, still using "Plaguespreader Zombie" and "Imperial Iron Wall", this card can create a helpless burn otk, if adding any card like "Cannon Soldier", "Toon Cannon Soldier" or a "Mass Driver" and any card in your hand to the combo. Activate the Imperial Iron Wall, then tribute Plaguespreader Zombie to inflict damage to your opponent. Return the card in your hand to the top of your deck with the cost of Plaguespreader Zombie to Special Summon it from the GY. Draw the card again with Card of Safe Return's effect and keep repeating this until you burn your opponent's LP for good.