This is a list of Monster Cards with 2450 DEF.
- For a list of monsters with 2450 ATK, see 2450 ATK Monster Cards.
OCG/TCG Monster Cards with 2450 DEF
| Japanese name | Primary type | Secondary type | Attribute | Type | Level/ Rank | ATK | |
|---|---|---|---|---|---|---|---|
| Cosmo Brain | コスモブレイン | Effect Monster | DARK | Spellcaster | 7 | 1500 | |
| Cosmo Queen | コスモクイーン | Normal Monster | DARK | Spellcaster | 8 | 2900 | |
| Cosmo Queen the Queen of Prayers | 祈りの女王－コスモクイーン | Effect Monster | DARK | Spellcaster | 8 | 2900 | |
| Gem-Knight Amethyst | ジェムナイト・アメジス | Effect Monster Fusion Monster | EARTH | Aqua | 7 | 1950 | |
| Gizmek Orochi, the Serpentron Sky Slasher | 機巧蛇－叢雲遠呂智 | Effect Monster | DARK | Machine | 8 | 2450 | |
| Orgoth the Relentless | ゴッド・オーガス | Effect Monster | EARTH | Warrior | 7 | 2500 | |
| Saffira, Divine Dragon of the Voiceless Voice | 粛声なる竜神サフィラ | Effect Monster Ritual Monster | LIGHT | Dragon | 7 | 2550 |
Anime Monster Cards with 2450 DEF
| Japanese name | Primary type | Secondary type | Attribute | Type | Level/ Rank | ATK | |
|---|---|---|---|---|---|---|---|
| The Dark Ruler | 冥界の魔王 ハ・デス | Effect Monster | DARK | Fiend | 6 | ??? | |
| Gem-Knight Crystal | ジェムナイト・クリスタ | Normal Monster | EARTH | Rock | 7 | ??? | |
| Giga Gagagigo | ギガ・ガガギゴ | Normal Monster | WATER | Reptile | 5 | ??? | |
| Javelin Beetle | ジャベリンビートル | Ritual Monster | EARTH | Insect | 8 | ??? | |
| Sword Hunter | ソードハンター | Effect Monster | EARTH | Warrior | 7 | ??? |