Card Appearances:De-Fusion

Yu-Gi-Oh!

 * Yugi used this card to defuse Strings' Humanoid Worm Drake. Since then, it has been used in many of Yugi's Duels.


 * Marik used this to separate himself from "The Winged Dragon of Ra".

Yu-Gi-Oh! GX

 * This card appeared while Chumley was building his deck in episode 8.
 * This card was thrown into the water by Chazz Princeton in episode 12.
 * Frequently used by Jaden Yuki as a response to opponents attacking his Fusion Monsters. Note that in the anime, using De-Fusion in this way results in attacks "missing", whereas in the real game a Replay would occur and at least one of the monsters would be destroyed.
 * Zane Truesdale frequently uses a similiar tactic with this card and his Cyber Dragon fusions.
 * Jaden Yuki used this in his Duel against Nightshroud. Nightshroud equipped "Attachment Dragon" to "Elemental Hero Rampart Blaster". Jaden used "De-Fusion" to seperate "Rampart Blaster" into its Fusion components, hence destroying "Attachment Dragon".
 * Alexis Rhodes set this card during her tag duel with Jaden Yuki against Chancellor Sheppard and Ms. Dorothy, but was unable to activate it.
 * Syrus Truesdale had this card in his deck as well.
 * Princess Rose used this card in her duel with Jaden.
 * Frantz used this card to separate himself from The Winged Dragon of Ra in his duel with Jaden..
 * This card appears in the GX Japanese closing song, Borderline Battle.

Video games

 * Salida Noula uses this in Yu-Gi-Oh! 5D's Stardust Accelerator.