Forum:Card Destruction and Chaining

I was reading through the Wikia and think we've have been playing something terrilbly wrong. We've been playing that sinc eyou resonve a chain backwards that cards like Mystical Space Typhoon and Even monster cards like Trap Reactor destroy cards that they are infact not activated. But, when reading the Wikia that seems not to be the case. Have we been wrong all this time?